| Saturday | January 01 2022 | New Year's Day | Federal Holiday |
| Thursday | January 06 2022 | Epiphany | Christian |
| Friday | January 07 2022 | Orthodox Christmas Day | Orthodox |
| Thursday | January 13 2022 | Stephen Foster Memorial Day | Observance |
| Friday | January 14 2022 | Orthodox New Year | Orthodox |
| Friday | January 14 2022 | Lee-jackson Day | State Holiday |
| Monday | January 17 2022 | Tu Bishvat/tu B'shevat | Jewish Holiday |
| Monday | January 17 2022 | Martin Luther King Jr. Day | Federal Holiday |
| Monday | January 17 2022 | Idaho Human Rights Day | State Holiday |
| Monday | January 17 2022 | Civil Rights Day | State Holiday |
| Wednesday | January 19 2022 | Robert E. Lee's Birthday | State Holiday |
| Saturday | January 29 2022 | Kansas Day | Observance |
| Tuesday | February 01 2022 | National Freedom Day | Observance |
| Tuesday | February 01 2022 | Chinese New Year | Observance |
| Wednesday | February 02 2022 | Groundhog Day | Observance |
| Friday | February 04 2022 | National Wear Red Day | Observance |
| Sunday | February 06 2022 | Super Bowl | Sporting Event |
| Friday | February 11 2022 | Lincoln's Birthday Observed | State Holiday |
| Saturday | February 12 2022 | Lincoln's Birthday | Local Observance |
| Monday | February 14 2022 | Valentine's Day | Observance |
| Tuesday | February 15 2022 | Susan B. Anthony's Birthday | Local Observance |
| Wednesday | February 16 2022 | Elizabeth Peratrovich Day | Local Observance |
| Monday | February 21 2022 | Daisy Gatson Bates Day | State Holiday |
| Monday | February 28 2022 | Linus Pauling Day | Local Observance |
| Tuesday | March 01 2022 | Shrove Tuesday/mardi Gras | Observance, Christian |
| Tuesday | March 01 2022 | St. David's Day | Observance, Christian |
| Tuesday | March 01 2022 | Town Meeting Day | State Holiday |
| Tuesday | March 01 2022 | Isra And Mi'raj | Muslim |
| Wednesday | March 02 2022 | Texas Independence Day | State Holiday |
| Wednesday | March 02 2022 | Read Across America Day | Observance |
| Wednesday | March 02 2022 | Ash Wednesday | Christian |
| Friday | March 04 2022 | Employee Appreciation Day | Observance |
| Sunday | March 13 2022 | Daylight Saving Time Starts | Clock Change/daylight Saving Time |
| Thursday | March 17 2022 | St. Patrick's Day | Observance, Christian |
| Thursday | March 17 2022 | Purim | Jewish Holiday |
| Sunday | March 20 2022 | March Equinox | Season |
| Friday | March 25 2022 | Maryland Day | Local Observance |
| Friday | March 25 2022 | Prince Jonah Kuhio Kalanianaole Day Observed | State Holiday |
| Saturday | March 26 2022 | Prince Jonah Kuhio Kalanianaole Day | State Holiday |
| Monday | March 28 2022 | Seward's Day | State Holiday |
| Tuesday | March 29 2022 | National Vietnam War Veterans Day | Observance |
| Friday | April 01 2022 | Pascua Florida Day Observed | Local Observance |
| Saturday | April 02 2022 | Pascua Florida Day | Local Observance |
| Sunday | April 03 2022 | Ramadan Starts | Muslim |
| Wednesday | April 06 2022 | National Tartan Day | Observance |
| Sunday | April 10 2022 | Palm Sunday | Christian |
| Tuesday | April 12 2022 | National Library Workers' Day | Observance |
| Wednesday | April 13 2022 | Thomas Jefferson's Birthday | Observance |
| Thursday | April 14 2022 | Maundy Thursday | Christian |
| Friday | April 15 2022 | Father Damien Day | Local Observance |
| Friday | April 15 2022 | Emancipation Day Observed | State Holiday |
| Saturday | April 16 2022 | Passover (first Day) | Jewish Holiday |
| Saturday | April 16 2022 | Holy Saturday | Christian |
| Sunday | April 17 2022 | Easter Sunday | Observance, Christian |
| Monday | April 18 2022 | Boston Marathon | Sporting Event |
| Monday | April 18 2022 | Easter Monday | Observance, Christian |
| Monday | April 18 2022 | Tax Day | Observance |
| Monday | April 18 2022 | Patriot's Day | State Holiday |
| Thursday | April 21 2022 | San Jacinto Day | State Holiday |
| Friday | April 22 2022 | Orthodox Good Friday | Orthodox |
| Friday | April 22 2022 | Oklahoma Day | Local Observance |
| Saturday | April 23 2022 | Last Day Of Passover | Jewish Holiday |
| Saturday | April 23 2022 | Orthodox Holy Saturday | Orthodox |
| Sunday | April 24 2022 | Orthodox Easter | Orthodox |
| Monday | April 25 2022 | Orthodox Easter Monday | Orthodox |
| Tuesday | April 26 2022 | Confederate Heroes' Day | Local Observance |
| Wednesday | April 27 2022 | Yom Hashoah | Jewish Commemoration |
| Wednesday | April 27 2022 | Administrative Professionals Day | Observance |
| Thursday | April 28 2022 | Lailat Al-qadr | Muslim |
| Thursday | April 28 2022 | Take Our Daughters And Sons To Work Day | Observance |
| Friday | April 29 2022 | Arbor Day | State Holiday |
| Sunday | May 01 2022 | Law Day | Observance |
| Sunday | May 01 2022 | Loyalty Day | Observance |
| Sunday | May 01 2022 | Lei Day | Local Observance |
| Tuesday | May 03 2022 | Eid Al-fitr | Muslim |
| Wednesday | May 04 2022 | Kent State Shootings Remembrance | Local Observance |
| Wednesday | May 04 2022 | Rhode Island Independence Day | Local Observance |
| Thursday | May 05 2022 | National Day Of Prayer | Observance |
| Thursday | May 05 2022 | Yom Ha'atzmaut | Jewish Holiday |
| Thursday | May 05 2022 | Cinco De Mayo | Observance |
| Friday | May 06 2022 | Kentucky Oaks | Sporting Event |
| Friday | May 06 2022 | National Nurses Day | Observance |
| Friday | May 06 2022 | Military Spouse Appreciation Day | Observance |
| Saturday | May 07 2022 | National Explosive Ordnance Disposal (eod) Day | Observance |
| Saturday | May 07 2022 | Kentucky Derby | Sporting Event |
| Sunday | May 08 2022 | Mother's Day | Observance |
| Sunday | May 08 2022 | Truman Day | State Holiday |
| Sunday | May 08 2022 | Victory In Europe Day | Observance |
| Monday | May 09 2022 | Truman Day Observed | State Holiday |
| Tuesday | May 10 2022 | Confederate Memorial Day | State Holiday |
| Tuesday | May 10 2022 | Primary Election Day | State Holiday |
| Sunday | May 15 2022 | Peace Officers Memorial Day | Observance |
| Thursday | May 19 2022 | Lag Baomer | Jewish Holiday |
| Friday | May 20 2022 | National Defense Transportation Day | Observance |
| Saturday | May 21 2022 | Armed Forces Day | Observance |
| Saturday | May 21 2022 | Preakness Stakes | Sporting Event |
| Sunday | May 22 2022 | National Maritime Day | Observance |
| Sunday | May 22 2022 | Harvey Milk Day | Local Observance |
| Wednesday | May 25 2022 | Emergency Medical Services For Children Day | Observance |
| Wednesday | May 25 2022 | National Missing Children's Day | Observance |
| Thursday | May 26 2022 | Ascension Day | Christian |
| Monday | May 30 2022 | Memorial Day | Federal Holiday |
| Wednesday | June 01 2022 | Statehood Day | Local Observance |
| Sunday | June 05 2022 | Pentecost | Christian |
| Sunday | June 05 2022 | Shavuot | Jewish Holiday |
| Monday | June 06 2022 | D-day | Observance |
| Monday | June 06 2022 | Whit Monday | Christian |
| Monday | June 06 2022 | Jefferson Davis' Birthday | State Holiday |
| Friday | June 10 2022 | Kamehameha Day Observed | State Holiday |
| Saturday | June 11 2022 | Kamehameha Day | State Holiday |
| Saturday | June 11 2022 | Belmont Stakes | Sporting Event |
| Sunday | June 12 2022 | Trinity Sunday | Christian |
| Sunday | June 12 2022 | Bunker Hill Day | Local Observance |
| Tuesday | June 14 2022 | Army Birthday | Observance |
| Tuesday | June 14 2022 | Flag Day | Observance |
| Thursday | June 16 2022 | Corpus Christi | Christian |
| Sunday | June 19 2022 | Father's Day | Observance |
| Sunday | June 19 2022 | Juneteenth | Local Observance |
| Monday | June 20 2022 | West Virginia Day | State Holiday |
| Monday | June 20 2022 | American Eagle Day | Observance |
| Tuesday | June 21 2022 | June Solstice | Season |
| Monday | July 04 2022 | Independence Day | Federal Holiday |
| Sunday | July 10 2022 | Eid Al-adha | Muslim |
| Wednesday | July 13 2022 | Nathan Bedford Forrest Day | Local Observance |
| Thursday | July 14 2022 | Bastille Day | Observance |
| Sunday | July 24 2022 | Pioneer Day | State Holiday |
| Sunday | July 24 2022 | Parents' Day | Observance |
| Monday | July 25 2022 | Pioneer Day Observed | State Holiday |
| Wednesday | July 27 2022 | National Korean War Veterans Armistice Day | Observance |
| Saturday | July 30 2022 | Muharram | Muslim |
| Monday | August 01 2022 | Colorado Day | Local Observance |
| Thursday | August 04 2022 | Coast Guard Birthday | Observance |
| Sunday | August 07 2022 | Tisha B'av | Jewish Holiday |
| Sunday | August 07 2022 | Purple Heart Day | Observance |
| Monday | August 08 2022 | Victory Day | State Holiday |
| Monday | August 15 2022 | Assumption Of Mary | Christian |
| Tuesday | August 16 2022 | Bennington Battle Day | State Holiday |
| Friday | August 19 2022 | Hawaii Statehood Day | State Holiday |
| Friday | August 19 2022 | National Aviation Day | Observance |
| Sunday | August 21 2022 | Senior Citizens Day | Observance |
| Friday | August 26 2022 | Women's Equality Day | Observance |
| Saturday | August 27 2022 | Lyndon Baines Johnson Day | State Holiday |
| Monday | September 05 2022 | Labor Day | Federal Holiday |
| Friday | September 09 2022 | California Admission Day | Local Observance |
| Saturday | September 10 2022 | Carl Garner Federal Lands Cleanup Day | Observance |
| Sunday | September 11 2022 | Patriot Day | Observance |
| Sunday | September 11 2022 | National Grandparents Day | Observance |
| Friday | September 16 2022 | National Pow/mia Recognition Day | Observance |
| Friday | September 16 2022 | Constitution Day And Citizenship Day Observed | Observance |
| Saturday | September 17 2022 | Constitution Day And Citizenship Day | Observance |
| Saturday | September 17 2022 | National Cleanup Day | Observance |
| Sunday | September 18 2022 | Air Force Birthday | Observance |
| Thursday | September 22 2022 | Emancipation Day | Local Observance |
| Thursday | September 22 2022 | September Equinox | Season |
| Friday | September 23 2022 | Native American Day | Local Observance |
| Sunday | September 25 2022 | Gold Star Mother's Day | Observance |
| Monday | September 26 2022 | Rosh Hashana | Jewish Holiday |
| Monday | October 03 2022 | Child Health Day | Observance |
| Tuesday | October 04 2022 | Feast Of St Francis Of Assisi | Christian |
| Wednesday | October 05 2022 | Yom Kippur | Jewish Holiday |
| Saturday | October 08 2022 | The Prophet's Birthday | Muslim |
| Sunday | October 09 2022 | Leif Erikson Day | Observance |
| Monday | October 10 2022 | First Day Of Sukkot | Jewish Holiday |
| Monday | October 10 2022 | Columbus Day | Federal Holiday |
| Monday | October 10 2022 | Native Americans' Day | Local Observance |
| Thursday | October 13 2022 | Navy Birthday | Observance |
| Saturday | October 15 2022 | White Cane Safety Day | Observance |
| Saturday | October 15 2022 | Sweetest Day | Observance |
| Sunday | October 16 2022 | Last Day Of Sukkot | Jewish Holiday |
| Monday | October 17 2022 | Shmini Atzeret | Jewish Holiday |
| Monday | October 17 2022 | Boss's Day | Observance |
| Tuesday | October 18 2022 | Simchat Torah | Jewish Holiday |
| Tuesday | October 18 2022 | Alaska Day | State Holiday |
| Monday | October 24 2022 | Diwali/deepavali | Observance, Hinduism |
| Friday | October 28 2022 | Nevada Day | State Holiday |
| Monday | October 31 2022 | Halloween | Observance |
| Tuesday | November 01 2022 | All Saints' Day | Christian |
| Wednesday | November 02 2022 | All Souls' Day | Christian |
| Sunday | November 06 2022 | Daylight Saving Time Ends | Clock Change/daylight Saving Time |
| Sunday | November 06 2022 | New York City Marathon | Sporting Event |
| Tuesday | November 08 2022 | Election Day | State Holiday |
| Thursday | November 10 2022 | Marine Corps Birthday | Observance |
| Friday | November 11 2022 | Veterans Day | Federal Holiday |
| Thursday | November 24 2022 | Thanksgiving Day | Federal Holiday |
| Friday | November 25 2022 | Acadian Day | State Holiday |
| Friday | November 25 2022 | Presidents' Day | State Holiday |
| Friday | November 25 2022 | Black Friday | Observance |
| Friday | November 25 2022 | Lincoln's Birthday/lincoln's Day | State Holiday |
| Friday | November 25 2022 | American Indian Heritage Day | State Holiday |
| Friday | November 25 2022 | Day After Thanksgiving | State Holiday |
| Friday | November 25 2022 | Family Day | State Holiday |
| Friday | November 25 2022 | State Holiday | State Holiday |
| Sunday | November 27 2022 | First Sunday Of Advent | Christian |
| Monday | November 28 2022 | Cyber Monday | Observance |
| Thursday | December 01 2022 | Rosa Parks Day | Local Observance |
| Tuesday | December 06 2022 | St Nicholas Day | Observance |
| Wednesday | December 07 2022 | Pearl Harbor Remembrance Day | Observance |
| Thursday | December 08 2022 | Feast Of The Immaculate Conception | Christian |
| Monday | December 12 2022 | Feast Of Our Lady Of Guadalupe | Christian |
| Tuesday | December 13 2022 | National Guard Birthday | Observance |
| Thursday | December 15 2022 | Bill Of Rights Day | Observance |
| Saturday | December 17 2022 | Pan American Aviation Day | Observance |
| Saturday | December 17 2022 | Wright Brothers Day | Observance |
| Monday | December 19 2022 | Chanukah/hanukkah (first Day) | Jewish Holiday |
| Wednesday | December 21 2022 | December Solstice | Season |
| Saturday | December 24 2022 | Christmas Eve | Observance, Christian |
| Sunday | December 25 2022 | Christmas Day | Federal Holiday |
| Monday | December 26 2022 | Last Day Of Chanukah | Jewish Holiday |
| Monday | December 26 2022 | Kwanzaa (first Day) | Observance |
| Monday | December 26 2022 | Christmas Day Observed | Federal Holiday |
| Monday | December 26 2022 | Day After Christmas Day | State Holiday |
| Friday | December 30 2022 | New Year's Eve Observed | State Holiday |
| Saturday | December 31 2022 | New Year's Eve | Observance |